Wan-Bissaka is one of the most highly-rated young players in European football and had an excellent first full season at Selhurst Park.
Ole Gunnar Solskjaer is desperate to overhaul his squad after a disastrous end to their season, winning just two of their last 12 matches in all competitions and has identified the right-back as one of his top priorities.
United legend Neville, who made 602 appearances for the club over 19 years, has backed his former side in their quest for Wan-Bissaka despite the £40million price tag.
“He’s a massive talent and the club, to be fair, have always signed young, emerging British talent,” he told the Evening Standard.
“I don’t think that should change and it would seem to me that the club would like to go back down that route and he is one.
“The price is always going to be big because clubs are wise now to it, you can’t pinch players off clubs for £5m or £6m.